A website offers lots of quotes on the subject. A definition:
The holiness of the berdache has to do with Indian views that everything that exists is a reflection of the spiritual. If a person is different from the average individual, this means that the spirit must have taken particular care in creating this person....[B]y this reasoning, such an individual must be especially close to the spirits.
Incidentally, Transamerica has little of the "freakishness" you might expect in a transgender movie. It's really about relationships--people bonding on a road trip. And everyone in it did a great job. Huffman deserved an Oscar for her performance more than Reese Witherspoon did.
Rob's rating: 8.5 of 10. See it for its Native core.